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A heart expert at Johns Hopkins is calling for all women with a waistline measuring more than 35 inches to get an annual check-up and detailed risk assessment for heart problems because excess abdominal fat, even in the mildly obese and overweight, leads more than a third of women to underestimate their lifetime risk of having a heart attack, stroke or chest pain (angina.)

Johns Hopkins scientists report success in significantly suppressing levels of the “hunger hormone” ghrelin in pigs using a minimally invasive means of chemically vaporizing the main vessel carrying blood to the top section, or fundus, of the stomach. An estimated 90 percent of the body’s ghrelin originates in the fundus, which can’t make the hormone without a good blood supply.

Jeremy Nathans, M.D., Ph.D., professor of molecular biology and genetics and ophthalmology, and King-Wai Yau, Ph.D., professor of neuroscience and ophthalmology, have been awarded the 2008 António Champalimaud Vision Award by the Champalimaud Foundation in Portugal for their “ground-breaking discoveries in the laboratory that enhance our knowledge and understanding of vision.”

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Jeff W.M. Bulte, Ph.D., professor of radiology, biomedical engineering and chemical and biomolecular engineering in the Johns Hopkins Russell H. Morgan Department of Radiology and Radiological Science, is one of 38 U.S. scientists to win one of the National Institutes of Health new EUREKA (for Exceptional, Unconventional Research Enabling Knowledge Acceleration) grants.

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People who walk on a treadmill even years after stroke damage can significantly improve their health and mobility, changes that reflect actual “rewiring” of their brains, according to research spearheaded at Johns Hopkins.